Anaemia during pregnancy as a risk factor for iron-deficiency anaemia in infancy : a case-control study in Jordan.
Background A high prevalence of 50-65% iron-deficiency anaemia in mothers and infants in Jordan was reported by the United Nations Relief and Works Agency (UNRWA) in 1990.
Iron-deficiency in infancy has been shown to delay cognitive and psychomotor development with long-term consequences.
While socioeconomic deprivation and inadequate nutrition are known underlying factors, it is unclear whether iron endowment at birth is compromised when mothers are anaemic, further jeopardizing iron status during infancy.
A prospective case-control study of infants from birth to one year was conducted in a lower middle-class urban setting in Amman, Jordan.
The study objective was to examine the relationship between maternal anaemia and iron-deficiency anaemia during infancy.
Method A sample of 107 anaemic (Hb<11 g/dl) and 125 non-anaemic mothers was selected at 37 weeks'gestation and matched for age and parity, and infant data at birth obtained.
The infants were reviewed at 3,6,9 and 12 months, to assess growth, current nutrition, infection rates and iron status.
The main outcome measure was the incidence of iron-deficiency anaemia in the two groups of infants, defined in the study as Hb<11 g/dl and either plasma ferritin<12 mcg/l or zinc protoporphyrin>35 mcg/dl.
Results Iron endowment in cord blood samples appeared similar between the two groups.
The incidence of iron-deficiency anaemia was very high in these infants, at 72% by research criteria, (51% if Hb<10. (...)
Mots-clés Pascal : Anémie ferriprive, Gestation, Mère, Epidémiologie, Facteur risque, Enfant, Homme, Jordanie, Asie, Etude cas témoin, Hémopathie, Sidéropénie
Mots-clés Pascal anglais : Iron deficiency anemia, Pregnancy, Mother, Epidemiology, Risk factor, Child, Human, Jordan, Asia, Case control study, Hemopathy, Sideropenia
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0339933
Code Inist : 002B19A01. Création : 14/12/1999.