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  1. House dust mite avoidance for children with asthma in homes of low-income families.

    Article - En anglais

    Background 

    Home exposure to high levels of house dust mite allergen has been shown to aggravate airways reactivity and asthma.

    Objective 

    The purpose of this study was to determine whether specific house dust mite control measures could reduce exposure levels and asthma severity.

    Methods 

    This double-blinded, randomized trial compared asthma progression over 1 year in children whose homes received standard environmental control intervention with those whose homes received aggressive intervention for dust mite elimination.

    The primary end point was doubling in PD20 methacholine.

    Results 

    Symptom scores and quality-of-life scores were similar for the standard and aggressive intervention groups.

    PD20 methacholine doubling occurred in 9 members of the aggressive intervention group vs 4 control patients (P<. 05).

    Dust mite levels decreased in the aggressive intervention homes compared with the standard intervention homes (P<. 05).

    Conclusion 

    Aggressive dust mite intervention decreased dust mite levels and improved bronchial hyperresponsiveness.

    Mots-clés Pascal : Asthme, Allergie, Enfant, Homme, Revenu individuel, Faible, Statut socioéconomique, Acaridae, Acaridida, Acariformes, Acari, Arachnida, Arthropoda, Invertebrata, Evitement, Etats Unis, Amérique du Nord, Amérique, Efficacité, Education santé, Santé et environnement, Hyperréactivité, Bronche, Prévention, Appareil respiratoire pathologie, Bronchopneumopathie obstructive, Immunopathologie

    Mots-clés Pascal anglais : Asthma, Allergy, Child, Human, Personal income, Low, Socioeconomic status, Acaridae, Acaridida, Acariformes, Acari, Arachnida, Arthropoda, Invertebrata, Avoidance, United States, North America, America, Efficiency, Health education, Health and environment, Hyperreactivity, Bronchus, Prevention, Respiratory disease, Obstructive pulmonary disease, Immunopathology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0338651

    Code Inist : 002B06C02. Création : 14/12/1999.