Air pollution. Conference. Genoa, ITA, 1998/09/28.
Glutaraldehyde and formaldehyde are found in the hospital environment at higher concentrations than those to which the general population is exposed.
Their possible advcrse health effects are therefore very important to those working in certain parts of hospitals and to patients in the hospitals whose health status may be compromised.
Both compounds are irritant and can cause sensilisation.
There are virtually no published data on animal toxicological studies on glutaraldehyde but for formaldehyde there are a number of animal studies which indicate that exposure to high concentrations of the vapour causes cytotoxic changes in the nasal mucosa which can lead to carcinoma.
There is, however, no convincing reason to consider formaldehyde a human carcinogen since prolonged exposure to concentrations causing cytolethality does not occur in hospital or indeed in occupational settings.
It would seem sensible to control the concentrations of both these aldehydes well below the level at which significant rritation and cytotoxicity occur by extraction of the vapours at the workplace and the provision of adequate ventilation elsewhere thus allowing the continued use of these two valuable chemicals.
Mots-clés Pascal : Glutaral, Formaldéhyde, Pollution air, Milieu hospitalier, Toxicité, Homme, Exposition professionnelle, Médecine travail, Personnel sanitaire, Irritation, Sensibilisation, Carcinogène, Prévention, Animal
Mots-clés Pascal anglais : Glutaral, Formaldehyde, Air pollution, Hospital environment, Toxicity, Human, Occupational exposure, Occupational medicine, Health staff, Irritation, Sensitization, Carcinogen, Prevention, Animal
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0338584
Code Inist : 002B03M02. Création : 14/12/1999.