To investigate attitudes to clinical research amongst potential research participants.
Two medical out-patient clinics and the background population.
A total of 508 randomly selected citizens in Copenhagen County (64% responded) and 200 consecutive patients attending the out-patient clinics (64% responded).
Attitudes toward different aspects of clinical research.
Positive attitudes toward medical research were disclosed.
The majority found scientific testing necessary, although only a minority considered participation a moral obligation.
Both personal benefits and altruistic motives for participation were highly rated, whereas former positive experiences from trial participation had only minor impact on decisions.
Several respondents stated former trial participation had changed their attitudes negatively.
Lack of feedback of results was of major importance for this change.
Attitudes are significantly influenced by the presence of independent research ethics committees, whereas trial technicalities such as drawing lots and blinding was found problematic by only a few respondents.
Altruistic motives of physicians to conduct trials were highly rated by a majority of respondents, but the motive of promoting doctors'careers was also judged important.
Respondents rated nondiscomforting procedures as acceptable or having only a small impact or strain on their, lives. (...)
Mots-clés Pascal : Essai clinique, Ethique, Attitude, Population, Observation, Questionnaire, Enquête, Homme
Mots-clés Pascal anglais : Clinical trial, Ethics, Attitude, Population, Observation, Questionnaire, Survey, Human
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0335829
Code Inist : 002B30A09. Création : 16/11/1999.