Hepatitis C virus infection risk factors in patients admitted in hospital emergency departments in Picardy. Value of oriented screening based on recommendations of the Direction Générale de la Santé.
Objective and design Oriented hepatitis C virus (HCV) screening on the basis of transfusion, previous or current parenteral drug addiction, invasive procedures, and in family members of patients with hepatitis C, was recommended in France by the'Direction Générale de la Santé' (DGS).
The aim of this study was to estimate the frequency of these risk factors in patients admitted in hospital emergency departments in Picardy.
Methods Between 1 June and 31 July 1996, physicians of the emergency units of seven hospitals in Picardy were asked to question admitted patients about risk factors mentioned in the DGS recommendations, and to suggest a screening test when at least one of these risk factors was present Results Among 1648 patients, 68.7% had at least one of these risk factors.
Screening was accepted by 723 patients, 58.7% of those with at least one risk factor, and more than 70% of those with history of transfusion and/or drug addiction.
It was immediately performed in 451, and 2.4% had anti-HCV antibodies.
The prevalence of anti-HCV antibodies was 1.5% in patients without history of transfusion or drug addiction and 7.9% in those with at least one of these two risk factors.
Conclusion Oriented screening based on transfusion or drug addiction history seems to have better efficiency than the screening policy recommended by the DGS.
Poor reliability of answers about medical history was observed probably because of stress related to emergency circumstances. (...)
Mots-clés Pascal : Hépatite virale C, Virose, Infection, Virus hépatite C, Hepacivirus, Flaviviridae, Virus, Dépistage, Service urgence, Incidence, Facteur risque, Epidémiologie, Homme, Picardie, France, Europe, Appareil digestif pathologie, Foie pathologie
Mots-clés Pascal anglais : Viral hepatitis C, Viral disease, Infection, Hepatitis C virus, Hepacivirus, Flaviviridae, Virus, Medical screening, Emergency department, Incidence, Risk factor, Epidemiology, Human, Picardie, France, Europe, Digestive diseases, Hepatic disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0321006
Code Inist : 002B30A01A2. Création : 16/11/1999.