This population-based study examined the effect of all major congenical anomalics on the mortality of White and Black infants by infant ses, birthweight, gestational age, and lethality of the anomaly.
The study also determined the total contribution of anomatics to infant inortality Methods.
California Birth Defects Monitoring Program data were merged with linked birth-death files for 278646 singleton non-Hispanie White and Diack infants born in 1983 through 1986.
Malformed infants were compared with nonmalformed infants to determine the effect of anomalies on mortality.
The presence of any congenital anomaly increased mortality 9.0-fold (95% CI=73.11.13 for Black infants and 17.8-fold (95% CI=16.2,19.8) for White infants Even « non-ltehal » anomalies increased mortality up to 8.9-fold Overnil, anomalics coniributed to 33% of White infant deaths, to 19% of Black infant deaths, and to over 60% of deaths among Black and White neonates weighing over 1499 g. Conclusions.
The contribation of congenital anomalies to mortality of both low (<2500 g) and normal-birth-weight infants is substantially higher than previously estimated representing a large public health problem for both Black and White infants.
Mots-clés Pascal : Malformation, Congénital, Nouveau né, Homme, Race, Blanc, Noir américain, Facteur risque, Mortalité, Tendance, Etats Unis, Amérique du Nord, Amérique, Epidémiologie, Prévalence, Poids naissance, Nouveau né pathologie
Mots-clés Pascal anglais : Malformation, Congenital, Newborn, Human, Race, White, Black American, Risk factor, Mortality, Trend, United States, North America, America, Epidemiology, Prevalence, Birth weight, Newborn diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0312403
Code Inist : 002B30A03C. Création : 16/11/1999.