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  1. Collagenous colitis : a long-term follow-up study.

    Article - En anglais

    Objective Collagenous colitis was first described in 1976.

    It is a rare disorder and the long-term course and prognosis of the disease are unknown.

    The aim of this study was to evaluate the course of the disease more than 5 years after the diagnosis.

    Design A retrospective follow-up of patients with collagenous colitis diagnosed during the period 1979-1990.

    Methods All examinations performed at the time of diagnosis were reviewed and the clinical courses of the patients were determined by evaluation of the medical records.

    At a follow-up visit in 1996 complete histories were obtained and conventional laboratory tests were performed.

    Results Two men and 22 women aged 20-82 years with collagenous colitis were identified.

    At the time of diagnosis, extensive investigation did not reveal other gastrointestinal diseases.

    At the time of follow-up, six patients had died from diseases unrelated to collagenous colitis, 10 patients suffered from chronic or intermittent diarrhoea, and four patients had been without gastrointestinal symptoms for the last 2-10 years.

    None of the patients developed colorectal cancer or chronic inflammatory bowel disease.

    Four patients were lost to follow-up.

    Conclusion Collagenous colitis is a benign disease, most often with a chronic course.

    No association with other gastrointestinal diseases was found.

    Mots-clés Pascal : Colite collagène, Etude longitudinale, Long terme, Histopathologie, Exploration clinique, Pronostic, Danemark, Europe, Homme, Appareil digestif pathologie, Intestin pathologie, Anatomopathologie

    Mots-clés Pascal anglais : Collagenous colitis, Follow up study, Long term, Histopathology, Clinical investigation, Prognosis, Denmark, Europe, Human, Digestive diseases, Intestinal disease, Pathology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0311783

    Code Inist : 002B13B03. Création : 16/11/1999.