Objective Collagenous colitis was first described in 1976.
It is a rare disorder and the long-term course and prognosis of the disease are unknown.
The aim of this study was to evaluate the course of the disease more than 5 years after the diagnosis.
Design A retrospective follow-up of patients with collagenous colitis diagnosed during the period 1979-1990.
Methods All examinations performed at the time of diagnosis were reviewed and the clinical courses of the patients were determined by evaluation of the medical records.
At a follow-up visit in 1996 complete histories were obtained and conventional laboratory tests were performed.
Results Two men and 22 women aged 20-82 years with collagenous colitis were identified.
At the time of diagnosis, extensive investigation did not reveal other gastrointestinal diseases.
At the time of follow-up, six patients had died from diseases unrelated to collagenous colitis, 10 patients suffered from chronic or intermittent diarrhoea, and four patients had been without gastrointestinal symptoms for the last 2-10 years.
None of the patients developed colorectal cancer or chronic inflammatory bowel disease.
Four patients were lost to follow-up.
Conclusion Collagenous colitis is a benign disease, most often with a chronic course.
No association with other gastrointestinal diseases was found.
Mots-clés Pascal : Colite collagène, Etude longitudinale, Long terme, Histopathologie, Exploration clinique, Pronostic, Danemark, Europe, Homme, Appareil digestif pathologie, Intestin pathologie, Anatomopathologie
Mots-clés Pascal anglais : Collagenous colitis, Follow up study, Long term, Histopathology, Clinical investigation, Prognosis, Denmark, Europe, Human, Digestive diseases, Intestinal disease, Pathology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0311783
Code Inist : 002B13B03. Création : 16/11/1999.