As part of the SENTRY Antimicrobial Surveillance Program, 1562 bacterial isolates were recovered from hospitalized patients with skin and soft tissue infections (SSTIs) in 30 United States (U.S.) and 8 Canadian medical centers between October and December, 1997.
The overall rank order of recovery of the six most common pathogens was Staphylococcus aureus (42.6%)>Pseudomonas aeruginosa (11.3%)>Enterococcus spp. (8.1%)>Escherichia coli (7.2%)>Enterobacter spp. (5.2%)>bêta-hemolytic streptocci (5.1%). With one exception, essentially the same order was observed in both the U.S. and Canada.
The single exception was the Enterococcus group, which were the third most common isolate in the U.S. (9.6%), but the seventh most common isolate in Canada (3.7).
Of note, 24.0% of S. aureus isolates were oxacillin resistant ; vancomycin was uniformly active.
Vancomycin resistance among Enterococcus spp. (16.5%) was observed only in the U.S. Several antimicrobial agents remained broadly active for SSTI isolates of P. aeruginosa, including meropenem, amikacin, tobramycin, and piperacillin with or without tazobactam.
Imipenem resistance (MICs, >= 8 mug/mL) was observed in 11.9% of isolates of P. aeruginosa and ceftazidime, and cefepime had equivalent activity (85.2% and 85.8% susceptible, respectively).
Numerous bêta-lactams, aminoglycosides and fluoroquinolones were broadly active against E. coli SSTI isolates (i.e.<5% resistance). (...)
Mots-clés Pascal : Bactérie, Homme, Bactériose, Infection, Peau, Partie molle, Epidémiologie, Surveillance sanitaire, Prévalence, Sensibilité résistance, Antibactérien, Antibiotique, Test sensibilité médicamenteuse, In vitro, Concentration minimale inhibitrice, Etats Unis, Amérique du Nord, Amérique, Canada
Mots-clés Pascal anglais : Bacteria, Human, Bacteriosis, Infection, Skin, Soft tissue, Epidemiology, Sanitary surveillance, Prevalence, Sensitivity resistance, Antibacterial agent, Antibiotic, Drug susceptibility test, In vitro, Minimum inhibitory concentration, United States, North America, America, Canada
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0311587
Code Inist : 002B02S02. Création : 16/11/1999.