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  1. Fulltext. Great expectations : Historical perspectives on genetic breast cancer testing.

    Article - En anglais


    Women who test positive for a genctie brease cancer marker may have more than a 50% chance of developing the disease.

    Although past screening technologies have sought to identify actual breast cancers, as opposed to predisposition, the history of screening may help predict the societal response to geactic testing For decades, educational messages have enconraged women to find breast cancers as early as possible.

    Such messages have fostered the popular assumption that immediately discovered and treated breast cancers are necessarily more curable, Research, however, has shown that screening improves the prognosis of some-but not all-breast concets, and also that it may lead to unnecessary interventions, The decholony between the adverfised value of early detection and its actual utility has caused particular controversy in the United States, where the cultural climate emphesizes the importance of obtaining all possible medical information and acting on it Early detection has probably helped to lower overall breast cancer mortality.

    But it has proven hard to praise aggressive screening without exaggerating its nerits.

    Women considering genetic breast cancer testing should weigh the benefits and limitations of early knowledge.

    Mots-clés Pascal : Tumeur maligne, Glande mammaire, Homme, Femelle, Dépistage, Prédisposition, Génétique, Perspective, Bénéfice, Limite, Ethique, Etats Unis, Amérique du Nord, Amérique, Glande mammaire pathologie

    Mots-clés Pascal anglais : Malignant tumor, Mammary gland, Human, Female, Medical screening, Predisposition, Genetics, Perspective, Profit, Limit, Ethics, United States, North America, America, Mammary gland diseases

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0311083

    Code Inist : 002B20E02. Création : 16/11/1999.