logo BDSP

Base documentaire


  1. Chlamydia pneumoniae as a triggering infection in reactive arthritis trig.

    Article - En anglais

    Objective

    To determine the role of Chlamydia pneumoniae as a triggering infection in reactive arthritis (ReA).

    Methods

    Sixty patients with acute arthritis were screened for the evidence of triggering infections.

    In all patients, bacterial stool cultures, culture of Chlamydia trachomatis in urethra/cervix, and/or bacterial serology were studied.

    Chlamydia pneumoniae antibodies were measured by specific microimmunofluorescence test.

    Results

    Thirty-five of 60 patients fulfilled the diagnostic criteria for ReA.

    Thirty-one patients had microbial/serological evidence of preceding infection due to Salmonella, Yersinia, Campylobacter or Chlamydia trachomatis, or they had enteritis or urethritis prior to arthritis.

    Four additional patients had high antibody titre for C. pneumoniae.

    Three of these four patients had preceding lower respiratory symptoms, and were positive for HLA-B27.

    The clinical picture of C. pneumoniae-positive ReA patients was similar to that of ReA patients with other definite aetiology.

    Conclusion

    Chlamydia pneumoniae is a triggering factor in ~ 10% of patients with acute ReA.

    Mots-clés Pascal : Arthrite réactionnelle, Infection, Pathogénie, Chlamydia pneumoniae, Chlamydiaceae, Chlamydiales, Bactérie, Exploration microbiologique, Immunofluorescence, Epidémiologie, Prévalence, Homme, Antigène, Anticorps, Bactériose, Système ostéoarticulaire pathologie, Rhumatisme inflammatoire, Spondylarthropathie

    Mots-clés Pascal anglais : Reactive arthritis, Infection, Pathogenesis, Chlamydia pneumoniae, Chlamydiaceae, Chlamydiales, Bacteria, Microbiological investigation, Immunofluorescence, Epidemiology, Prevalence, Human, Antigen, Antibody, Bacteriosis, Diseases of the osteoarticular system, Inflammatory joint disease, Spondylarthropathy

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0307528

    Code Inist : 002B15D. Création : 16/11/1999.