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  1. Sad, glad, or mad hearts ? epidemiological evidence for a causal relationship between mood disorders and coronary artery disease.

    Article - En anglais


    To examine the epidemiological evidence to determine if there is sufficient support for the hypothesis that mood disorders convey a risk factor in the pathogenesis of coronary artery disease (CAD).


    Based on a review of the related research on Type A behavioral pattern (TABP) and other variables such as anger and hostility and their relationship to coronary artery disease (CAD), the findings were analyzed to ascertain any clinical patterns or similarities between behaviors of Type A and those in mood disorders.

    Using the given epidemiological criteria for a causal relationship, the association between the mood and coronary artery disease was explored.


    There are similar symptoms and behaviors noted among Type A, manic, cyclothymic and hyperthymic individuals.

    There is sufficient historical and contemporaneous epidemiological evidence to support the notion that mood disorders confer risk for CAD, but it is premature to describe it as a causative factor.

    Depressive symptoms and general mood disorders emerged as toxic risk factors for CAD.


    This article presents only a selective literature review, and it is limited by an epidemiological analyses of secondary sources.

    The impact of this limitation on the interpretation of the analyses is discussed. (...)

    Mots-clés Pascal : Etat dépressif, Comportement type A, Relation associative, Cardiopathie coronaire, Pathogénie, Facteur risque, Epidémiologie, Article synthèse, Personnalité, Homme, Trouble humeur, Appareil circulatoire pathologie

    Mots-clés Pascal anglais : Depression, Type A behavior, Associative relation, Coronary heart disease, Pathogenesis, Risk factor, Epidemiology, Review, Personality, Human, Mood disorder, Cardiovascular disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0307213

    Code Inist : 002B18B03. Création : 16/11/1999.