Pneumocystis carinii pneumonia in patients with connective tissue diseases : The role of hospital experience in diagnosis and mortality.
Pneumonia due to Pneumocystis carinii has been increasingly reported in patients with connective tissue diseases, but the frequency of this complication is not known.
We sought to determine the frequency of P carinii pneumonia (PCP) in patients with connective tissue diseases, and to determine the role that a hospital's acquired immunodeficiency syndrome (AIDS) - related experience may have in the diagnosis of PCP in these patients.
We used a state hospitalization registry to identify all patients with PCP and either rheumatoid arthritis, systemic lupus erythematosus, Wegener's granulomatosis, polymyositis, dermatomyositis, polyarteritis nodosa, or scleroderma who had an emergent or urgent hospitalization in California from 1983 to 1994.
We compared patient and hospital characteristics between these patients and patients with connective tissue diseases hospitalized with other types of pneumonia.
Two hundred twenty-three patients with connective tissue diseases were diagnosed with PCP in the 12-year study period.
The frequency of PCP ranged from 89 cases/10,000 hospitalizations/year in patients with Wegener's granulomatosis to 2 cases/10,000 hospitalizations/year in patients with rheumatoid arthritis. (...)
Mots-clés Pascal : Tissu conjonctif maladie mixte, Complication, Infection, Pneumonie, Pneumocystis carinii, Fungi Imperfecti, Fungi, Thallophyta, Diagnostic, Epidémiologie, Fréquence, Homme, Hospitalisation, Peau pathologie, Appareil circulatoire pathologie, Appareil respiratoire pathologie, Système ostéoarticulaire pathologie, Muscle strié pathologie, Maladie système, Maladie autoimmune, Poumon pathologie
Mots-clés Pascal anglais : Sharp syndrome, Complication, Infection, Pneumonia, Pneumocystis carinii, Fungi Imperfecti, Fungi, Thallophyta, Diagnosis, Epidemiology, Frequency, Human, Hospitalization, Skin disease, Cardiovascular disease, Respiratory disease, Diseases of the osteoarticular system, Striated muscle disease, Systemic disease, Autoimmune disease, Lung disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0306329
Code Inist : 002B07. Création : 16/11/1999.