Study objective-To explore the association between job characteristics and plasma fibrinogen concentrations.
Setting-The Greater Stockholm area.
Subjects-A total of 1018 men and 490 women aged 45-70 who were randomly selected from the general population during 1992-1994.
They were all employed and had no history of myocardial infarction.
Main results-The self reported job characteristics were measured by a Swedish version of the Karasek demand-control questionnaire.
For inferred scoring of job characteristics, psychosocial exposure categories (job control and psychological demands) were assigned by linking each subject's occupational history with a work organisation exposure matrix.
Job strain was defined as the ratio between demands and control.
In univariate analyses, expected linear trends were found in three of four tests of association between high plasma fibrinogen and low control (the self reported score for women and the inferred score for both sexes), in one of four tests of association between high plasma fibrinogen and high demands (the inferred score for women) and in two of four tests of association between high plasma fibrinogen and job strain (the inferred score for both sexes).
Multiple logistic regression analyses showed that men in the inferred job strain group have an increased risk of falling into the increased plasma fibrinogen concentration group (above median level of the distribution) (odds ratio (OR) 1. (...)
Mots-clés Pascal : Fibrinogène, Plasma sanguin, Concentration, Activité professionnelle, Epidémiologie, Corrélation, Homme, Suède, Europe
Mots-clés Pascal anglais : Fibrinogen, Blood plasma, Concentration, Professional activity, Epidemiology, Correlation, Human, Sweden, Europe
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0301405
Code Inist : 002B30A01A2. Création : 16/11/1999.