Background/Aims-Quality of life is an important determinant of the effectiveness of health technologies, but it has rarely been assessed in patients receiving home parenteral nutrition (HPN).
Patients/Methods-The non-disease specific sickness impact profile (SIP) and the disease specific inflammatory bowel disease questionnaire (IBDQ) were used on a cohort of 49 patients receiving HPN, and the results compared with those for 36 non-HPN patients with either anatomical (<200 cm) or functional (faecal energy excretion>2.0 MJ/day (-488 kcal/day)) short bowel.
In the HPN patients the SIP scores were worse (higher) overall (17 (13)% upsilon 8 (9)%) and with regard to physical (13 (15)% upsilon 5 (8)%) and psychosocial (14 (12)% upsilon 9 (11)%) dimensions and independent categories (20 (12)% upsilon 9 (8)%) compared with the non-HPN patients (means (SD) ; all p<0.001).
The IBDQ scores were worse (lower) in the HPN patients overall (5.0 (4.3-5.7) upsilon 5.6 (4.8-6.2)) and with regard to systemic symptoms (3.8 (2.8-5.4) upsilon 5.2 (3.9-5.9)) and emotional (5.3 (4.4-6.2) upsilon 5.8 (5.4-6.4)) and social (4.3 (3.4-5.5) upsilon 4.8 (4.5-5.8)) function (median (25-75%) ; all p<0.05), but only tended to be worse with regard to bowel symptoms (5.2 (4.8-6.1) upsilon 5.7 (4.9-6.4), p=0.08).
HPN also reduced quality of life in patients with a stoma, whereas a stoma did not reduce quality of life among the non-HPN patients. (...)
Mots-clés Pascal : Entérite Crohn, Rectocolite ulcérohémorragique, Sickness Impact Profile Gilson, Nutrition, Voie parentérale, A domicile, Qualité vie, Etude cohorte, Questionnaire, Facteur sociodémographique, Evaluation, Homme, Danemark, Europe, Appareil digestif pathologie, Intestin pathologie, Maladie inflammatoire, Organisation santé
Mots-clés Pascal anglais : Crohn disease, Ulcerative colitis, Sickness Impact Profile Gilson, Nutrition, Parenteral administration, At home, Quality of life, Cohort study, Questionnaire, Sociodemographic factor, Evaluation, Human, Denmark, Europe, Digestive diseases, Intestinal disease, Inflammatory disease, Public health organization
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0301194
Code Inist : 002B26F. Création : 16/11/1999.