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  1. Association of waist circumference with ApoB to ApoAl ratio in black and white Americans.

    Article - En anglais

    BACKGROUND 

    Although numerous studies have demonstrated obesity as an aspect of the insulin resistance syndrome in cardiovascular disease (CVD), the mechanism is not clear.

    Central adiposity, acting through many CVD risk factors, including, plasma glucose, insulin, total cholesterol, low density lipoprotein-cholesterol (LDL-C) and lipoprotein moities-apolipoprotein B (ApoB), apolipoprotein A-I (ApoAl), by atherogenic and thrombotic mechanisms has been proposed as a possible mechanism.

    In this study, we examined the relationship between central fat distribution (defined by waist circumference) and the ratio of these lipoproteins (ApoB/ApoAl).

    SUBJECTS AND METHODS 

    Association between ApoB/ApoAl ratio and waist circumference was compared in Blacks (n=854) and Whites (n=2552) using the NHANES III population-based samples.

    Correlation analyses and multiple regression analyses were used to determine the association between ApoB/ApoAl and waist circumference, controlling for age, body mass index (BMI), race, gender, plasma glucose, insulin, serum triglyceride and total cholesterol.

    RESULTS 

    Adjusting for age, ApoB/ApoAl was significantly correlated with waist circumference (Black men : r=0.38, White men : r=0.26, Black women : r=0.20, White women : r=0.36) (all P<0.01). (...)

    Mots-clés Pascal : Obésité, Masse grasse, Distribution, Anthropométrie, Etude comparative, Apolipoprotéine B, Apolipoprotéine AI, Plasma sanguin, Insuline, Résistance tissu cible, Lipémie, Origine ethnique, Epidémiologie, Caucasoïde, Adulte, Homme, Personne âgée, Négroïde, Etats Unis, Amérique du Nord, Amérique, Etat nutritionnel, Trouble nutrition, Hormone pancréatique, Endocrinopathie

    Mots-clés Pascal anglais : Obesity, Fat mass, Distribution, Anthropometry, Comparative study, Apolipoprotein B, Apolipoprotein AI, Blood plasma, Insulin, Target tissue resistance, Lipemia, Ethnic origin, Epidemiology, Caucasoid, Adult, Human, Elderly, Negroid, United States, North America, America, Nutritional status, Nutrition disorder, Pancreatic hormone, Endocrinopathy

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0300794

    Code Inist : 002B30A01A2. Création : 16/11/1999.