New injectable antimicrobial agents are generally costly and broad-spectrum.
Overusage results in unnecessary economic loss and multi-drug resistant organisms.
Effective strategies for decreasing costs without compromising patient care are required.
This study aimed to evaluate the economic impact ofa system using an antimicrobial order form to assist rational usage of expensive antimicrobial agents.
The study was performed during 1988-1996 at a 900-bed, tertiary-care, medical school hospital in Bangkok.
The target drugs were 3 costly, broad-spectrum antibacterial drugs, namely imipenem, vancomycin, and injectable ciprofloxacin.
The restriction of these 3 drugs was started in 1992 and was extended to netilmicin and ceftazidime in 1995.
A filled antimicrobial order form (AOF) was required by pharmacists before dispensing the drugs.
The AOF guided the physicians to give explicit information about anatomic diagnosis, etiologic diagnosis, and suspectcd antimicrobial resistance patterns of the organisms.
It also contained information about indications of the restricted drugs.
The filled forms were audited daily during working days by the chairman of The Hospital Antibiotic Committee.
Feedback was given to the prescribers by infectious disease specialists at least twice a week.
The strategy was endorsed by the executive committee of the hospital.
Impact of AOF without endorsement, audit and feedback as evaluated in 1996. (...)
Mots-clés Pascal : Consommation, Médicament, Antibiotique, Economie santé, Forme injectable, Thaïlande, Asie
Mots-clés Pascal anglais : Consumption, Drug, Antibiotic, Health economy, Injectable form, Thailand, Asia
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0298843
Code Inist : 002B30A01C. Création : 16/11/1999.