The increasing concern over human exposure to arsenic in West Bengal and Bangladesh has necessitated the development of a rapid method for determination of trace levels of arsenic in water and biological samples.
We have developed a simple indigenous flow injection hydride generation atomic absorption spectrometry (FI-HG-AAS) system for the determination of arsenic in parts-per-billion levels in water and biological samples.
The technique is fast, simple, and highly sensitive.
The accuracy and precision of the method were evaluated by spiking known amounts of arsenic and analyzing different types of environmental and biological standard reference materials.
The organic matter in a biological sample was destroyed by acid digestion and dry ashing technique.
We analyzed thousands of tubewell water samples from the affected districts of West Bengal and Bangladesh.
Most of the water samples contained a mixture of arsenite and arsenate and in none of them could we detect methylated arsenic.
We also analyzed thousands of urine (inorganic arsenic and its metabolites), hair, and nail samples and hundreds of skin-scale and blood samples of people drinking arsenic-contaminated water and showing arsenical skin lesions.
Quality control was assessed by interlaboratory analysis of hair samples.
An understanding of arsenic toxicity and metabolism requires quantitation of individual arsenic species. (...)
Mots-clés Pascal : Analyse chimique, Analyse multiélément, Analyse trace, Arsenic Composé organique, Arséniate, Arsénite, Echantillon environnement, Milieu biologique, Spectrométrie absorption atomique, Injection en écoulement, Hydruration, Enrichissement chimique, Spéciation, Contrôle milieu ambiant, Pollution chimique, Toxicologie, Bengla Desh, Asie, Inde, Arsinique acide(diméthyl), Arsonique acide(méthyl)
Mots-clés Pascal anglais : Chemical analysis, Multicomponent analysis, Trace analysis, Arsenic Organic compounds, Arsenates, Arsenites, Environmental materials, Biological medium, Atomic absorption spectrometry, Flow injection, Hydridation, Chemical enrichment, Speciation, Environmental control, Chemical pollution, Toxicology, Bangladesh, Asia, India
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0294224
Code Inist : 001C04C. Création : 16/11/1999.