Compelling evidence suggests a causal relation between exposure to parental cigarette smoking and respiratory symptoms during childhood.
Still, the roles of prenatal versus postnatal parental smoking need clarification.
In this study, the authors assessed the effects of passive smoking on respiratory symptoms in a cohort of over 1,000 children born during 1980-1984.
The children were enrolled in the Tucson Children's Respiratory Study in Tucson, Arizona, and were followed from birth to age 11 years.
The population was generally middle class and consisted of two main ethnic groups, non-Hispanic Whites (75%) and Hispanics (20%), reflecting Tucson's population.
Information on parental smoking and on wheeze and cough in their children was elicited from parents by using questionnaires at five different surveys.
Data were analyzed both cross-sectionally and by using the generalized estimation equation approach, a longitudinal mixed-effects model.
The best-fitting model indicated that maternal prenatal but not postnatal smoking was associated with current wheeze (odds ratio=2.3,95% confidence interval 1.4-3.8) independently of a family history of asthma, socioeconomic factors, and birth weight.
This effect was time dependent and significant only below age 3 years ; although independent of gender, the association was stronger for girls (odds ratio=3.6,95% confidence interval 1.6-8.0).
Cough was not associated with parental smoking during the first decade of life. (...)
Mots-clés Pascal : Etats Unis, Amérique du Nord, Amérique, Epidémiologie, Prévalence, Enfant, Homme, Sexe, Toux, Tabagisme passif, Etude cohorte, Etude longitudinale, Questionnaire, Tabagisme, Mère, Gestation, Pollution air, Appareil respiratoire pathologie, Age 0-10ans, Wheezing
Mots-clés Pascal anglais : United States, North America, America, Epidemiology, Prevalence, Child, Human, Sex, Cough, Passive smoking, Cohort study, Follow up study, Questionnaire, Tobacco smoking, Mother, Pregnancy, Air pollution, Respiratory disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0292043
Code Inist : 002B11B. Création : 16/11/1999.