Study on the internal exposure of chimney sweeps to hazardous substances.
During their occupational activities chimney sweeps are exposed to different levels of hazardous substances formed during combustion.
The aim of this study was to evaluate the current internal exposure of chimney sweeps to hazardous substances.
Groups : Biological monitoring was carried out in chimney sweeps from three different regions of Germany (n=93) and from Poland (n=7).
The metabolite, 1-hydroxypyrene, and several hydroxylated phenanthrenes were determined in urine as indicators of exposure to polyeyelic aromatic hydrocarbons (PAH).
In addition, urinalysis was carried out with some of these chimney sweeps to detect aromatic amines (n=11).
The 1-hydroxypyrene concentrations ranged in the total group from below the detection limit (0.1 mug/l) and 12.8 mug/l (Median : 0,7 mug/l).
The Polish chimney sweeps were found to be the group with the highest values.
There was a similar pattern of distribution for the phenanthrenes (median : 1-OH-phenanthrene : 0.46 mug/l ; sum of 2-and 9-OH-phenanthrene : 0.38 mug/l ; 3-OH-phenanthrene : 0.59 mug/l : 4-OH-phenanthrene : 0.042 mug/l).
In some cases, concentrations of aromatic amines above the valid reference values for occupationally non-exposed persons were observed.
A conspicuous finding was an increase in the concentration of various aromatic amines in the urine of a few persons.
(Maximum : p-Phenylenediamine : 240.6 mug/l : bêta-Naphthylamine : 13.1 mug/l ; Methylenediamine : 128. (...)
Mots-clés Pascal : Exposition professionnelle, Médecine travail, Composé aromatique polycyclique, Surveillance biologique, Marqueur biologique, Liquide biologique, Urine, Composé aromatique, Amine, Homme, Etude cohorte, Ramoneur, Pyrène(1-hydroxy)
Mots-clés Pascal anglais : Occupational exposure, Occupational medicine, Polycyclic aromatic compound, Biological monitoring, Biological marker, Biological fluid, Urine, Aromatic compound, Amine, Human, Cohort study
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0290422
Code Inist : 002B03L06. Création : 16/11/1999.