This study determined potential associations of sociodemographic, lifestyle, health, and drug use factors known to affect bone metabolism with incident nonvertebral fractures.
The baseline sample consisted of 2,590 female, nonproxy subjects from the Duke Established Populations for Epidemiologic Studies of the Elderly, which focuses on five adjacent counties in the Piedmont area of North Carolina.
Information about potential risk factors was collected during a baseline in-home interview during 1986-1987.
Subsequent nonvertebral fractures were reported at follow-up interviews during the annual follow-up periods (1988-1993).
The authors used multivariate analyses in which weighted data were adjusted for sampling design.
After controlling for other potential confounding sociodemographic, lifestyle, health, and drug use factors, they found that African American race (adjusted odds ratio (OR)=0.43,95% confidence interval (Cl) 0.31-0.58), age (adjusted OR=1.04,95% Cl 1.01-1.06), alcohol consumption (adjusted OR=1.61,95% Cl 1.01-2.57), being underweight (adjusted OR=1.63,95% Cl 1.13-2.34), cognitive impairment (adjusted OR=1.67,95% Cl 1.12-2.48), impaired mobility (adjusted OR=1.15,95% Cl 1.03-1.29), and phenytoin use (adjusted OR=2.93,95% Cl 1.04-8.30) were associated with first fracture occurrence.
Similar findings were observed for nonhip, nonvertebral fractures. (...)
Mots-clés Pascal : Ostéoporose, Personne âgée, Homme, Femelle, Fracture, Os, Hanche, Poignet, Bras, Race, Noir américain, Statut socioéconomique, Facteur risque, Etats Unis, Amérique du Nord, Amérique, Epidémiologie, Incidence, Etude cohorte, Système ostéoarticulaire pathologie, Ostéopathie, Traumatisme
Mots-clés Pascal anglais : Osteoporosis, Elderly, Human, Female, Fracture, Bone, Hip, Wrist, Arm, Race, Black American, Socioeconomic status, Risk factor, United States, North America, America, Epidemiology, Incidence, Cohort study, Diseases of the osteoarticular system, Bone disease, Trauma
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0289537
Code Inist : 002B16H. Création : 16/11/1999.