A multi-modality assessment of peripheral nerve function in organophosphate-pesticide applicators.
Health effects from chronic, low-level exposure to organophosphate pesticides have not been studied extensively and are not well-established.
This report follows up a study in New York State in which a cohort of 90 male pesticide applicators were found to have increased vibration sensitivity thresholds, compared with a matched sample drawn from the general population.
This investigation examined the nature and extent of peripheral nerve abnormalities in a small subgroup of the original cohort.
Of the nine subjects studied, four had clinical evidence of peripheral neuropathic dysfunction, and one who was normal physiologically showed electrophysiological abnormalities.
The remaining four showed no clinical, electrophysiologic, or quantitative signs or other abnormalities.
This study adds to the growing evidence that organo-phosphates are toxic to the peripheral nervous system at levels of exposure that do not induce acute or subacute symptomatology.
Mots-clés Pascal : Exposition professionnelle, Médecine travail, Pesticide, Organophosphoré, Agriculture, Neuropathie périphérique, Toxicité, Evaluation, Homme
Mots-clés Pascal anglais : Occupational exposure, Occupational medicine, Pesticides, Organophosphorus compounds, Agriculture, Peripheral neuropathy, Toxicity, Evaluation, Human
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0289271
Code Inist : 002B03G. Création : 16/11/1999.