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  1. Depression and dementia : Comorbidities, identification, and treatment.

    Article - En anglais

    Depression is a highly prevalent concomitant of dementia.

    Concurrent depression (DD) can meet full criteria for a disorder or take the form of a depressive syndrome.

    Although phenomenologic overlap can confound diagnosis, careful assessment demonstrates that a true depressive component is present in a substantial percentage of dementia cases.

    DD has been associated with excess disability, increased caregiver burden, and greater mortality.

    Efficacy studies have demonstrated high placebo response rates, indicating transience of many depressive symptoms, and adverse cognitive effects of older antidepressants.

    Studies demonstrating that new antidepressants can be efficacious and improve cognitive functioning are reviewed.

    Mots-clés Pascal : Etat dépressif, Association morbide, Démence, Epidémiologie, Diagnostic, Traitement, Antidépresseur, Chimiothérapie, Article synthèse, Personne âgée, Homme, Trouble humeur, Psychotrope, Système nerveux central, Système nerveux pathologie, Encéphale pathologie, Maladie dégénérative

    Mots-clés Pascal anglais : Depression, Concomitant disease, Dementia, Epidemiology, Diagnosis, Treatment, Antidepressant agent, Chemotherapy, Review, Elderly, Human, Mood disorder, Psychotropic, Central nervous system, Nervous system diseases, Cerebral disorder, Degenerative disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0284003

    Code Inist : 002B18E. Création : 16/11/1999.