Earlier studies have shown that farmers are to a low degree sensitized to animal allergens.
We have measured the amount of cat (Fel d 1) and dog (Can f 1) in farm households and examined the relationship between exposure and sensitization to cat and dog allergens.
Dust samples from the homes of 403 farmers who had participated in an epidemiologic follow-up study on respiratory symptoms were analyzed for allergen content by two-site ELISA methods.
Fel d 1 was detected in 99.5% of the farmers'households ranging from 0.055 to 1455 mug/g dust in mattresses (GM 13.2) and to 3775 mug/g dust in living-room carpets (GM 17.1).
Can f 1 was detected in 90.6% of the households from 0.2 to 116 mug/g dust in mattresses (GM 2.0) and to 504 mug/g dust in carpets (GM 4.3).
Homes with pets present had the highest levels of the allergens (P<0.001).
A total of 8.4% and 7.4% of the farmers were sensitized to cat and dog, respectively.
A significant correlation was noted between exposure to the allergens and specific IgE to cat and dog, respectively (P<0.001).
Sensitization to cat (OR=4.9) and dog (OR=17.8) was significantly associated with asthma.
In spite of the abundance of Fel d 1 and Can f 1, farmers are only to a low degree sensitized to cats and dogs.
Mots-clés Pascal : Allergie, Allergène, Pneumallergène, Chien, Fissipedia, Carnivora, Mammalia, Vertebrata, Chat, Animal domestique, Environnement, Milieu rural, Agriculteur, Logement habitation, Etiologie, Epidémiologie, Suède, Europe, Homme, Exposition, Sensibilisation, Immunopathologie
Mots-clés Pascal anglais : Allergy, Allergen, Aeroallergen, Dog, Fissipedia, Carnivora, Mammalia, Vertebrata, Cat, Domestic animal, Environment, Rural environment, Farmer, Housing, Etiology, Epidemiology, Sweden, Europe, Human, Exposure, Sensitization, Immunopathology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0275829
Code Inist : 002B06C01. Création : 16/11/1999.