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  1. Exposure to an abundance of cat (Fel d 1) and dog (Can f 1) allergens in Swedish farming households.

    Article - En anglais


    Earlier studies have shown that farmers are to a low degree sensitized to animal allergens.

    We have measured the amount of cat (Fel d 1) and dog (Can f 1) in farm households and examined the relationship between exposure and sensitization to cat and dog allergens.


    Dust samples from the homes of 403 farmers who had participated in an epidemiologic follow-up study on respiratory symptoms were analyzed for allergen content by two-site ELISA methods.


    Fel d 1 was detected in 99.5% of the farmers'households ranging from 0.055 to 1455 mug/g dust in mattresses (GM 13.2) and to 3775 mug/g dust in living-room carpets (GM 17.1).

    Can f 1 was detected in 90.6% of the households from 0.2 to 116 mug/g dust in mattresses (GM 2.0) and to 504 mug/g dust in carpets (GM 4.3).

    Homes with pets present had the highest levels of the allergens (P<0.001).

    A total of 8.4% and 7.4% of the farmers were sensitized to cat and dog, respectively.

    A significant correlation was noted between exposure to the allergens and specific IgE to cat and dog, respectively (P<0.001).

    Sensitization to cat (OR=4.9) and dog (OR=17.8) was significantly associated with asthma.


    In spite of the abundance of Fel d 1 and Can f 1, farmers are only to a low degree sensitized to cats and dogs.

    Mots-clés Pascal : Allergie, Allergène, Pneumallergène, Chien, Fissipedia, Carnivora, Mammalia, Vertebrata, Chat, Animal domestique, Environnement, Milieu rural, Agriculteur, Logement habitation, Etiologie, Epidémiologie, Suède, Europe, Homme, Exposition, Sensibilisation, Immunopathologie

    Mots-clés Pascal anglais : Allergy, Allergen, Aeroallergen, Dog, Fissipedia, Carnivora, Mammalia, Vertebrata, Cat, Domestic animal, Environment, Rural environment, Farmer, Housing, Etiology, Epidemiology, Sweden, Europe, Human, Exposure, Sensitization, Immunopathology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0275829

    Code Inist : 002B06C01. Création : 16/11/1999.