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  1. Exposure to an abundance of cat (Fel d 1) and dog (Can f 1) allergens in Swedish farming households.

    Article - En anglais

    Background 

    Earlier studies have shown that farmers are to a low degree sensitized to animal allergens.

    We have measured the amount of cat (Fel d 1) and dog (Can f 1) in farm households and examined the relationship between exposure and sensitization to cat and dog allergens.

    Methods 

    Dust samples from the homes of 403 farmers who had participated in an epidemiologic follow-up study on respiratory symptoms were analyzed for allergen content by two-site ELISA methods.

    Results 

    Fel d 1 was detected in 99.5% of the farmers'households ranging from 0.055 to 1455 mug/g dust in mattresses (GM 13.2) and to 3775 mug/g dust in living-room carpets (GM 17.1).

    Can f 1 was detected in 90.6% of the households from 0.2 to 116 mug/g dust in mattresses (GM 2.0) and to 504 mug/g dust in carpets (GM 4.3).

    Homes with pets present had the highest levels of the allergens (P<0.001).

    A total of 8.4% and 7.4% of the farmers were sensitized to cat and dog, respectively.

    A significant correlation was noted between exposure to the allergens and specific IgE to cat and dog, respectively (P<0.001).

    Sensitization to cat (OR=4.9) and dog (OR=17.8) was significantly associated with asthma.

    Conclusions 

    In spite of the abundance of Fel d 1 and Can f 1, farmers are only to a low degree sensitized to cats and dogs.

    Mots-clés Pascal : Allergie, Allergène, Pneumallergène, Chien, Fissipedia, Carnivora, Mammalia, Vertebrata, Chat, Animal domestique, Environnement, Milieu rural, Agriculteur, Logement habitation, Etiologie, Epidémiologie, Suède, Europe, Homme, Exposition, Sensibilisation, Immunopathologie

    Mots-clés Pascal anglais : Allergy, Allergen, Aeroallergen, Dog, Fissipedia, Carnivora, Mammalia, Vertebrata, Cat, Domestic animal, Environment, Rural environment, Farmer, Housing, Etiology, Epidemiology, Sweden, Europe, Human, Exposure, Sensitization, Immunopathology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0275829

    Code Inist : 002B06C01. Création : 16/11/1999.