Tender points (TPs) and fibromyalgia (FM) may be precipitated by infections, but the frequency, associated characteristics, and predictors of these outcomes are unknown.
To determine if acute infectious mononucleosis (AIM) is associated with the development of TPs or FM acutely or during the subsequent 6 months ; if demographic, clinical, or psychosocial features predict TPs or FM ; and if TPs or FM correlate with nonrecovery.
A total of 150 subjects diagnosed as having AIM were assessed with physical examinations (including palpation of 18 TPs), laboratory tests, and measures of psychosocial and somatic functioning at enrollment and at 2 and 6 months.
Subjects also completed a structured psychiatric interview at the initial evaluation.
At presentation and at 2 and 6 months, the mean TP counts were 7.5,4.6, and 3.0, respectively ; at these time points, 19%, 3%, and 1% of subjects also met modified criteria for FM.
Tender points and degree of pain diminished over time following AIM.
Acutely, TPs were associated only with higher temperature (P<. 001).
Baseline features that predicted more TPs at 2 and 6 months were female sex, older age, less family social support, and more TPs at presentation.
Neither initial laboratory tests nor psychiatric disease or distress predicted TPs.
Differences between those who had and had not recovered at 6 months were found for the mean number of TPs (P<. (...)
Mots-clés Pascal : Fibromyalgie, Exploration clinique, Association, Mononucléose infectieuse, Virose, Infection, Aigu, Facteur prédictif, Facteur sociodémographique, Evaluation, Durée, Sensibilité, Ostéoarticulaire, Analyse statistique, Homme, Douleur, Système ostéoarticulaire pathologie, Muscle strié pathologie
Mots-clés Pascal anglais : Fibromyalgia, Clinical investigation, Association, Infectious mononucleosis, Viral disease, Infection, Acute, Predictive factor, Sociodemographic factor, Evaluation, Duration, Sensitivity, Osteoarticular, Statistical analysis, Human, Pain, Diseases of the osteoarticular system, Striated muscle disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0269924
Code Inist : 002B15I. Création : 16/11/1999.