Aims-To determine the clinical features of a large number of unselected UK hospital patients with confirmed septic arthritis and to determine those features associated with a poor outcome.
Setting-A single English Health District.
Patients-All patients admitted to hospital in Nottingham during the period 1 January 1982 to 31 December 1991 with confirmed septic arthritis were included.
Outcome measures-Death, osteomyelitis and recorded functional impairment.
The spectrum of causative organisms remains similar to that seen in previous studies with the Gram positive organisms Staphylococcus aureus and Streptococci responsible for 74% of cases, gonococcal infections though were less common.
Culture of joint aspirates and or blood were positive in 82% of cases, with the Gram stain demonstrating the causative organism in 50% of cases.
Pre-existing joint disease was evident in 35% of cases.
The mortality remains high at 11.5% with a significant additional morbidity of 31.6%. Multivariate analysis suggests that important predictors of death are : confusion at presentation, age >=65 years, multiple joint sepsis or involvement of the elbow joint, and of morbidity are : age >= 65 years, diabetes mellitus, open surgical drainage, and Gram positive infections other than S aureus.
Conclusions-Septic arthritis continues to be associated with a considerable degree of morbidity and mortality. (...)
Mots-clés Pascal : Arthrite, Articulation, Infection, Septicémie, Symptomatologie, Facteur risque, Epidémiologie, Pronostic, Morbidité, Mortalité, Homme, Système ostéoarticulaire pathologie, Arthropathie, Bactériose
Mots-clés Pascal anglais : Arthritis, Joint, Infection, Septicemia, Symptomatology, Risk factor, Epidemiology, Prognosis, Morbidity, Mortality, Human, Diseases of the osteoarticular system, Arthropathy, Bacteriosis
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0265081
Code Inist : 002B05B02J. Création : 16/11/1999.