Population distribution of six PCR-amplified loci in Madeira Archipelago (Portugal).
Frequency data of the short tandem repeat (STR) loci HUMTH01, HUMVWA31/A, HUMF13A1, HUMFES/FPS, D12S391 and HUMFIBRA/FGA were determined in blood stains obtained from a population of unrelated individuals from the Madeira Archipelago.
The observed genotype distribution showed no significant deviation from the Hardy-Weinberg equilibrium and there was no evidence for association of alleles among the six loci.
Population data showed a combined discrimination power of 0.9999998 and a chance of exclusion of 0.99597.
The frequencies are similar to those of other compared caucasian populations but significant differences were found between the Madeira population and Japanese, Chinese, Greenland Eskimos and Quechua Amerindians.
The six loci studied, together proved to be highly discriminating and valuable for forensic cases.
Mots-clés Pascal : Variabilité génétique, Génome, Locus, Génétique population, Réaction chaîne polymérase, Epidémiologie, Biologie moléculaire, Homme, Madère, Iles Atlantiques, Génétique
Mots-clés Pascal anglais : Genetic variability, Genome, Locus, Population genetics, Polymerase chain reaction, Epidemiology, Molecular biology, Human, Madeira, Atlantic Ocean Islands, Genetics
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0264451
Code Inist : 002B23A. Création : 16/11/1999.