Fel d 1 and Can f 1 in settled dust and airborne Fel d 1 in allergen avoidance day-care centres for atopic children in relation to number of pet-owners, ventilation and general cleaning.
Background Special day-care centres for atopic children have been established in Sweden.
Objective To study concentrations of cat (Fel d 1) and dog (Can f 1) allergens in settled dust and airborne cat allergen in day-care centres in relation to pet ownership among children and staff, ventilation and general cleaning.
Methods Twelve allergen avoidance day-care centres and 22 conventional day-care centres were included in the study.
Settled dust was collected and analysed with ELISA.
Airborne cat allergen levels were measured in eight allergen avoidance and seven conventional centres with a personal air sampler and analysed with an amplified ELISA.
Air change rate per hour (ACH) was measured.
A questionnaire which focused on keeping of cat and dog among staff and children and frequency of general cleaning was used.
Results In the allergen avoidance day-care centres neither children nor staff reported ownership of cats or dogs, compared with 21/22 of the conventional centres in which children and staff kept furred animals.
Fel d I and Can f 1 were found in settled dust in all day-care centres.
In the allergen avoidance compared with the conventional centres the concentrations of Fel d 1 and Can f 1 were lower, Fel d 1 : median 0.64 mug/g vs 5.45 mug/g and Can f 1 : 0.39 mug/g vs 2.51, both P<0.001, and airborne Fel d 1 was also lower in the allergen avoidance centres compared with the control centres, 1.51 ng/m3 vs 15.8 ng/m3, P=0.002. (...)
Mots-clés Pascal : Allergie, Prévention, Environnement, Allergène, Pneumallergène, Poussière maison, Chien, Fissipedia, Carnivora, Mammalia, Vertebrata, Chat, Animal domestique, Garderie enfant, Enfant, Homme, Suède, Europe, Immunopathologie
Mots-clés Pascal anglais : Allergy, Prevention, Environment, Allergen, Aeroallergen, House dust, Dog, Fissipedia, Carnivora, Mammalia, Vertebrata, Cat, Domestic animal, Day care center, Child, Human, Sweden, Europe, Immunopathology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0263115
Code Inist : 002B06C01. Création : 16/11/1999.