To estimate the prevalence of epilepsy in India by meta-analysis of previously published and unpublished studies and to determine patterns of epilepsy by using community-based studies.
We attempted to identify as many previously published and unpublished studies as possible on the prevalence of epilepsy in India.
The studies were assessed with regard to methods and definitions.
The prevalence rates for rural and urban populations and for men and women were calculated with a 95% confidence interval (CI).
The studies that provided details on age structure, age-specific rates, and patterns of epilepsy were chosen for meta-analysis.
Both crude values and age-standardized prevalence rates were calculated after accounting for heterogeneity.
Twenty studies were found involving a sample population of 598,910, among whom 3,207 had epilepsy.
This resulted in a crude prevalence of 5.35/1,000.
After a correction for heterogeneity due to interstudy variation, the overall prevalence per 1,000 (and its 95% CI) was 5.33 (4.25-6.41) ; with urban areas at 5.11 (3.49-6.73) ; rural areas, 5.47 (4.04-6.9) ; men, 5.88 (3.89-7.87) ; and women 5.51 (3.49-7.53).
After correction for the variability in estimates of heterogeneity, age-standardized rates (from five studies) revealed that the prevalence rates per 1,000 (and the 95% CI), were as follows :
overall, 5.59 (4.15-7.03) ;
men, 6.05 (3.79-8.31) ;
women, 5.18 (3.04-7.32) ;
urban, 6.34 (3.43-9.25) ;
rural, 4. (...)
Mots-clés Pascal : Epilepsie, Inde, Asie, Métaanalyse, Prévalence, Epidémiologie, Homme, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie
Mots-clés Pascal anglais : Epilepsy, India, Asia, Metaanalysis, Prevalence, Epidemiology, Human, Nervous system diseases, Central nervous system disease, Cerebral disorder
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0260137
Code Inist : 002B17A03. Création : 16/11/1999.