To determine the relation between placenta previa and male sex at birth, the authors conducted two types of analysis : 1) a historical cohort analysis of singleton live births in New Jersey hospitals during 1989-1992 (N=447,963) ; and 2) a meta-analysis of previously published studies on the subject.
For the cohort analysis, subject mother-infant dyads were identified from linked birth certificate and maternal and infant hospital claims data.
The infant's sex for mothers with an International Classification of Diseases, Ninth Revision, Clinical Modification, code of 641.0-641.1 for placenta previa (n=2,685) was compared with infant's sex for mothers without placenta previa (n=445,270).
For the meta-analysis, seven published articles were located and summary effects were calculated using both fixed-effect and random-effects models.
In the present cohort study, the male : female ratio at birth was significantly higher in women with placenta previa (1.19) than in those without placenta previa (1.05) (p<0.001).
The association of placenta previa with male sex persisted when the analysis was either stratified or adjusted for the effects of maternal age, maternal parity, maternal smoking during the index pregnancy, racelethnicity, the infant's gestational age, and the infant's birth weight. (...)
Mots-clés Pascal : Placenta praevia, Sexe, Ratio, Epidémiologie, Facteur risque, Nouveau né, Homme, Revue bibliographique, Gestation pathologie, Accouchement pathologie, Placenta pathologie
Mots-clés Pascal anglais : Placenta previa, Sex, Ratio, Epidemiology, Risk factor, Newborn, Human, Bibliographic review, Pregnancy disorders, Delivery disorders, Placenta diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0255050
Code Inist : 002B20F02. Création : 16/11/1999.