Adverse drug events in hospitalized patients : A comparison of doctors, nurses and patients as sources of reports.
This study investigated the relative value of adverse drug events reported by doctors, nurses and patients.
The study was conducted on a total of four wards : the paediatric and internal medicine wards (including geriatric patients) of two peripheral hospitals in the Netherlands.
Adverse drug events were collected by spontaneous reporting (doctor and nurse reports) and by daily ward visits, during which the patients were interviewed by a hospital pharmacist (patient reports).
Criteria for relative value of the reported adverse drug events were the number of potentially serious reactions, the number of reactions not mentioned in the patient information leaflet and the number of reactions reported to new drugs (5 years or less on the Dutch market).
No formal causality assessment was applied.
Over a period of 2 months in 1996 (Hospital I) and 2 months in 1997 (Hospital II) a total of 620 patients were included in the study and adverse drug events were reported in 179 (29%) of these cases.
Doctors reported a statistically significant larger number of serious (26% of all doctor reports ; odds ratio (OR) 3.2 ; confidence interval (CI) 1.2-8.7) and unknown (39% ; OR 2.5 ; CI 1.0-6.0) adverse drug events than patients themselves during the daily ward visit.
Doctors also reported more serious and unknown adverse drug events than nurses. (...)
Mots-clés Pascal : Effet secondaire, Toxicité, Médicament, Hospitalisation, Homme, Médecin, Infirmier, Malade, Etude cas, Compte rendu, Pharmacie hospitalière, Etude critique
Mots-clés Pascal anglais : Secondary effect, Toxicity, Drug, Hospitalization, Human, Physician, Nurse, Patient, Case study, Report, Hospital pharmacy, Critical study
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0254119
Code Inist : 002B02U10. Création : 16/11/1999.