By reviewing patient's records, we evaluated the sensitivity and specificity of the 1982 revised classification criteria for systemic lupus erythematosus on a cohort of 346 Norwegian patients with connective tissue disease, seen at a rheumatology referral center in the period 1986-95.
The patients with CTD other than SLE were used as controls.
The number of the 1982 revised classification criteria for SLE fulfilled by each individual patient was calculated.
Fifty-five of the 76 SLE patients (72%) met four or more criteria for SLE, giving a low sensitivity of 72%. Twenty-three of the 270 patients with CTD other than SLE (9%) met four or more criteria for SLE, giving an acceptable specificity of 91%. Applying the « revised/revised 1997 ACR criteria for SLE » the sensitivity would have increased to 78% and the specificity reduced to 89%. The sample of SLE patients wa characterized by mild disease with a low proportion of severe internal manifestations.
Mots-clés Pascal : Tissu conjonctif pathologie, Critère, Classification, Lupus érythémateux, Disséminé, Diagnostic, Epidémiologie, Norvège, Europe, Méthodologie, Sensibilité, Spécificité, Homme, Peau pathologie, Maladie système, Maladie autoimmune, Immunopathologie
Mots-clés Pascal anglais : Connective tissue disease, Criterion, Classification, Lupus erythematosus, Disseminated, Diagnosis, Epidemiology, Norway, Europe, Methodology, Sensitivity, Specificity, Human, Skin disease, Systemic disease, Autoimmune disease, Immunopathology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0253738
Code Inist : 002B07. Création : 16/11/1999.