Development of atherosclerosis over a 25 year period : an epidemiological autopsy study in males of 11 towns.
We conducted an analysis of the data from two epidemiological autopsy studies of atherosclerosis in men aged 20-59 years in 1963-66 (the first study, 7470 cases) and in 1985-88 (the second study, 9600 cases).
The investigations were performed in accordance with a special program of the World Health Organization in 11 town populations :
Irkutsk and Yakutsk (Russia),
Prague (Czech Republic),
Tallinn and Tartu (Estonia), and Kharkov and Yalta (Ukraine).
Native and non-native populations were studied separately in Ashkhabad, Bishkek, and Yakutsk.
Atherosclerosis was studied by the visual morphometrical method in the descending thoracic aorta, abdominal aorta and three main coronary arteries.
In each vessel the prevalence and extent (percent of intimal surface) of fatty streaks, fibrous plaques, complicated, calcified and also raised lesions (all lesions except fatty streaks) were determined.
Coronary stenosis was estimated in arteries as narrowed by more than 50%. Accelerated development of coronary atherosclerosis, especially in the 40-59 year age group, was noted in the second study in the male populations of most towns except Prague and Malmo.
In Prague the extent of raised lesions in coronary arteries was practically the same in both studies, in Malmo it decreased in the second study. (...)
Mots-clés Pascal : Athérosclérose, Homme, Mâle, Evolution, Epidémiologie, Autopsie, Suède, Europe, Europe Est, Russie, Eurasie, Exploration, Artère coronaire, Aorte, Appareil circulatoire pathologie, Vaisseau sanguin pathologie, Cardiopathie coronaire, Aorte pathologie, Artère pathologie
Mots-clés Pascal anglais : Atherosclerosis, Human, Male, Evolution, Epidemiology, Autopsy, Sweden, Europe, Eastern Europe, Russia, Eurasia, Exploration, Coronary artery, Aorta, Cardiovascular disease, Vascular disease, Coronary heart disease, Aortic disease, Arterial disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0246651
Code Inist : 002B12B01. Création : 16/11/1999.