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  1. A systematic overview of the use of diary cards, quality-of-life questionnaires, and psychometric tests in treatment trials of Helicobacter pylori-positive and - negative non-ulcer dyspepsia.

    Article - En anglais

    Background 

    Our aim was to evaluate the use of diary cards, quality-of-life questionnaires, and psychometric tests in treatment trials of non-ulcer dyspepsia.

    Methods 

    Data sources were a Medline search (up to 1966) and a manual search of five gastrointestinal journals (up to 1980) for original, randomized, double-blind, placebo-controlled trials with at least 20 patients which evaluated treatment regimens for non-ulcer dyspepsia.

    Results 

    Of the 67 eligible studies, 31 used diary cards.

    Diary cards were used alone in 15 of the 31 studies (48%), whereas the others (52%) also used a physician assessment.

    The symptoms assessed by diary cards were epigastric pain (100%), nausea/vomiting (65%), heartburn (52%), belching (39%), regurgitation (29%), fullness (29%), and bloating (23%). Forty-five per cent also recorded antacid use.

    Severity of outcome measures was assessed by a visual analogue scale in 5 of the 31 studies (16%), Likert scales in 17 studies (55%), and unclear methods in 3 studies (10%). For statistical analysis daily averages of symptoms were used in 5 of the 31 studies (16%), weekly averages in 11 studies (35%), and 2-week intervals during the treatment period in the rest, with some studies using a combination (such as daily and weekly averages).

    Only 3 of the 31 studies (8%) checked for compliance with diary card data.

    None of the studies mention anything about missing data and how this was handled. (...)

    Mots-clés Pascal : Dyspepsie, Fonctionnelle, Association morbide, Gastrite, Bactériose, Infection, Helicobacter pylori, Spirillaceae, Spirillales, Bactérie, Evaluation, Symptomatologie, Questionnaire, Qualité vie, Psychométrie, Efficacité traitement, Métaanalyse, Homme, Appareil digestif pathologie, Estomac pathologie

    Mots-clés Pascal anglais : Dyspepsia, Functional, Concomitant disease, Gastritis, Bacteriosis, Infection, Helicobacter pylori, Spirillaceae, Spirillales, Bacteria, Evaluation, Symptomatology, Questionnaire, Quality of life, Psychometrics, Treatment efficiency, Metaanalysis, Human, Digestive diseases, Gastric disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0245265

    Code Inist : 002B13B03. Création : 16/11/1999.