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  1. Fulltext. Methadone dosing, heroin affordability, and the severity of addiction.

    Article - En anglais


    Objectives This study sought to track changes in US heroin priees from 1988 to 1995 and to determine whether changes in the affordability of heroin were associated with changes in the use of heroin by theirs seeking methadone treatment, as indexed by methadone dose levels.


    Data on the price of heroin were from the Drug Enforcement Administration ; data on methadone doses were from surveys conducted in 1988,1990, and 1995 of 100 methadone maintenance centers Multivariable models that controlled for time and city effects were uscd in uncertain whether clinics in cities where heroin was less expensive had patients receiving highes doses of methadone, which would suggest that these patients had relatively higher physiological levels of opiate addiction owing to increased heroin use Results The amount of pure heroin contained in a $100 (US) purchase has increased on average 3-fold between 1988 and 1995.

    The average dose of methadone in clinics was positively associated with the affordability of local heroin (P<01).

    Conclusions When heroin prices fall, heroin addicts require mote methadone (a heroin substitute) to stabilize their addiction evidence that they are consuming more heroin.

    Mots-clés Pascal : Toxicomanie, Homme, Drogue illicite, Evaluation, Surveillance sanitaire, Relation, Prix vente, Héroïne, Traitement substitutif, Méthadone, Dosage, Etude multicentrique, Etats Unis, Amérique du Nord, Amérique, Epidémiologie

    Mots-clés Pascal anglais : Drug addiction, Human, Illicit drug, Evaluation, Sanitary surveillance, Relation, Selling price, Heroin, Replacement therapy, Methadone, Assay, Multicenter study, United States, North America, America, Epidemiology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0245231

    Code Inist : 002B18C05A. Création : 16/11/1999.