An extensive ultrasound and serologic study to investigate the prevalence of human cystic echinococcosis in Northern Libya.
A prevalence study of abdominal cystic echinococcosis (CE) was undertaken in the northwest, northcentral, and northeast regions of Libya.
A total of 36 villages along the coast were included, in which 20,220 people were screened by portable ultrasound.
Three hundred thirty-nine (1.7%) were diagnosed with CE.
There was no significant difference between CE prevalence rates in the three regions of Libya (mean=1.6%) ; however, intervillage rates were variable, ranging from 0% to 4.5%. The prevalence of CE increased significantly with age (P<0.0001) and females were significantly more affected (2%) than males (1.3%) (P<0.0001).
Cases of CE were distributed among 3.2% of housewives, 2.6% of farmers, 2.3% of male civil servants, 1.3% of female students, and 1.1% of male students.
Housewives (P<0.0001) and students (P<0.0001) were significantly more at risk for CE.
A statistically significant proportion (62% [210 of 339]) of CE cases kept dogs (P<0.0001).
Of the ultrasound-positive CE cases 69% (233 of 339) were antibody seropositive by ELISA using Echinococcus granulosus hydatid cyst fluid antigen B. Blood samples (n=10,096) collected onto filter papers were taken randomly from ultrasound-negative people who entered the study, of which 11.2% were found to be seropositive.
Seropositivity increased with age (P<0.0001), with females exhibiting higher seroprevalence than males for all age groups (P<0.0001). (...)
Mots-clés Pascal : Kyste hydatique, Echinococcose, Cestodose, Helminthiase, Parasitose, Infection, Echinococcus granulosus, Cestoda, Plathelmintha, Helmintha, Invertebrata, Prévalence, Exploration, Sérologie, Exploration ultrason, Abdomen, Dépistage, Campagne de masse, Homme, Libye, Afrique
Mots-clés Pascal anglais : Hydatid cyst, Echinococciasis, Cestode disease, Helminthiasis, Parasitosis, Infection, Echinococcus granulosus, Cestoda, Plathelmintha, Helmintha, Invertebrata, Prevalence, Exploration, Serology, Sonography, Abdomen, Medical screening, Mass campaign, Human, Libya, Africa
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0241581
Code Inist : 002B05E03A3. Création : 16/11/1999.