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  1. Possible implication of environmental hormones in the recent risk increase of cancers of the skin and the liver, but not of the female breast worldwide.

    Article - En anglais

    The invention of 2 contrasting terms « Western type cancer » and « non-Western type cancer » implies that the progress of Westernization of life style for a given population may find its reflection in the balance of cancer risk between a Western type cancer and a non-Western type cancer.

    Our recent investigation presented evidence to indicate that the incidence of cancers of all sites increased by 32.1% (males) and 18.0% (females) from early 1960s to mid 1980s in the world statistics, and that the observed risk increase of cancers of the skin and liver did not fit the definition of « Westernization effect ».

    It was suggested that the spread of environmental hormones could be related to the increased risks of 2 cancers.

    This study attempted to test the validity of the above statement by studying comparatively the epidemiological aspects of cancer of the skin, liver and breast, the latter being the reference tumor of the « Westernization effect ».

    Cancer risk for each tumor was expressed in terms of the age-specific incidence rate (ASIR) and age-adjusted incidence rate (AAIR).

    For mathematical reasons, both ASIR-and AAIR-data were transformed into their logarithms before statistical analysis.

    We prepared the world population model with a size of 38 population units to investigate the relation between reproductive activity and cancer risk. (...)

    Mots-clés Pascal : Tumeur maligne, Foie, Peau, Glande mammaire, Facteur risque, Hormone stéroïde sexuelle, Reproduction, Mode de vie, Monde Ouest, Monde, Homme, Appareil digestif pathologie, Foie pathologie, Peau pathologie, Glande mammaire pathologie

    Mots-clés Pascal anglais : Malignant tumor, Liver, Skin, Mammary gland, Risk factor, Sex steroid hormone, Reproduction, Life style, Western countries, World, Human, Digestive diseases, Hepatic disease, Skin disease, Mammary gland diseases

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0241004

    Code Inist : 002B04B. Création : 16/11/1999.