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  1. Diagnostik und Therapie des Mammakarzinoms seit Einführung des mammographischen Screenings in der flächendeckenden, ambulanten Versorgung des Grossherzogtums Luxemburg.

    Article - En allemand

    Traduction en anglais : Diagnosis and therapy of breast cancer since the population-wide introduction of a mammography screening programme in the ambulant health care system of Luxembourg.

    Introduction 

    The efficiency of mammography screening in highly specialized diagnostic centres has been well proven for the age group 50-64 years.

    Few data is available concerning the value of such a screening under decentralised, population-wide conditions.

    Since 1992, a mammography screening program (LMSP) organised in this way is being offered in Luxembourg to the age group 50-64 years.

    Materials and methods 

    The early outcome indicators of this screening programme were evaluated retrospectively.

    The pathological characteristics of all the diagnosed breast cancers, their diagnosis and their therapy before (1989) and after (1993) the introduction of the mammography screening programme were compared and analysed.

    Results 

    The early outcome indicators of Luxembourg's mammography screening programme were just below the comparable values of other specialised centres.

    Since the introduction of this programme one notes a significant increase in the number of open breast biopsies in comparison to the period before the screening programme (p=0.0001), with a highly significant increase in benign biospies (p=0.00001).

    The ratio cancer/all biopsies dropped non-significantly from 0.35 to 0.28 (p=0.09).

    Atypical proliferative hyperplasias and in situ carcinomas increased significantly in number (p=0.01) as did the number of early invasive cancers (p=0.0015).

    The lymph node status did not change significantly although there was an increase in node-negative tumours (p=0.11). (...)

    Mots-clés Pascal : Carcinome, Glande mammaire, Mammographie, Luxembourg, Europe, Traitement, Dépistage, Rétrospective, Diagnostic, Homme, Femelle, Tumeur maligne, Glande mammaire pathologie, Radiodiagnostic

    Mots-clés Pascal anglais : Carcinoma, Mammary gland, Mammography, Luxembourg, Europe, Treatment, Medical screening, Retrospective, Diagnosis, Human, Female, Malignant tumor, Mammary gland diseases, Radiodiagnosis

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0240119

    Code Inist : 002B20E02. Création : 16/11/1999.