Occupational risk factors of lung cancer : a hospital based case-control study.
Objectives-To investigate the relation between lung cancer and exposure to occupational carcinogens in a highly industrialised region in western Europe.
Methods-In a case-control study 478 cases and 536 controls, recruited from 10 hospitals in the Antwerp region, were interviewed.
Cases were male patients with histologically confirmed lung cancer ; controls were male patients without cancer or primary lung diseases.
Data were collected by questionnaires to obtain information on occupations, exposures, and smoking history.
Job titles were coded with the Office of Populations, Censuses and Surveys industrial classification.
Exposure was assessed by self report and by job-task exposure matrix.
Exposure odds ratios were calculated with logistic regression analysis adjusted for age, smoking history, and marital and socioeconomic status.
A job history in the categories manufacturing of transport equipment other than automobiles (for example, shipyard workers), transport support services (for example, dockers), and manufacturing of metal goods (for example, welders) was significantly associated with lung cancer (odds ratios (ORs) 2.3,1.6, and 1.6 respectively).
These associations were independent of smoking, education, civil, and economic status.
Self reported exposure to potential carcinogens did not show significant associations with lung cancer, probably due to non-differential misclassification. (...)
Mots-clés Pascal : Exposition professionnelle, Médecine travail, Industrie, Tumeur maligne, Bronchopulmonaire, Homme, Toxicité, Carcinogène, Facteur risque, Evaluation, Etude cas témoin, Comparaison interindividuelle, Activité professionnelle, Epidémiologie, Belgique, Europe, Appareil respiratoire pathologie, Poumon pathologie, Bronche pathologie
Mots-clés Pascal anglais : Occupational exposure, Occupational medicine, Industry, Malignant tumor, Bronchopulmonary, Human, Toxicity, Carcinogen, Risk factor, Evaluation, Case control study, Interindividual comparison, Professional activity, Epidemiology, Belgium, Europe, Respiratory disease, Lung disease, Bronchus disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0236108
Code Inist : 002B11A. Création : 16/11/1999.