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  1. Seasonal variation in stroke mortality rates.

    Article - En anglais

    Objective 

    To identify possible contributors to the seasonal variation in stroke mortality.

    Background 

    Stroke and respiratory disease mortality rates were calculated from vital statistics and census data for the United States from 1938 to 1988.

    State-specific average temperatures by month were derived from data obtained from the National Climatic Data Center for 1938 to 1987.

    Methods 

    Each time series was decomposed into a trend, a seasonal effect, and a residual effect.

    Multiple regression was used to fit both a trend and a seasonal harmonic series.

    Cross-correlation was used to assess the relationship between the residual time series.

    Results 

    There is a strong and consistent seasonal pattern of high stroke and respiratory disease mortality in the colder winter months.

    Stroke mortality was significantly and independently both positively associated with respiratory disease mortality and inversely associated with temperature.

    The sharp initial increases in both respiratory disease and stroke mortality in the late fall and early winter are synchronous, and the amplitudes are strongly associated, except for a saturation effect with extreme respiratory disease amplitudes.

    Conclusions 

    Seasonal change in stroke mortality is associated with seasonal variation in both respiratory disease and temperature.

    Respiratory disease and temperature may influence stroke mortality nonspuriously by affecting stroke case fatality, incidence, or both.

    Mots-clés Pascal : Accident cérébrovasculaire, Mortalité, Variation saisonnière, Température atmosphérique, Appareil respiratoire pathologie, Etats Unis, Amérique du Nord, Amérique, Epidémiologie, Evolution, Effet température, Homme, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie, Cérébrovasculaire pathologie, Appareil circulatoire pathologie, Vaisseau sanguin pathologie

    Mots-clés Pascal anglais : Stroke, Mortality, Seasonal variation, Atmospheric temperature, Respiratory disease, United States, North America, America, Epidemiology, Evolution, Temperature effect, Human, Nervous system diseases, Central nervous system disease, Cerebral disorder, Cerebrovascular disease, Cardiovascular disease, Vascular disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0235882

    Code Inist : 002B17C. Création : 16/11/1999.