Objective To examine fertility patterns in women who had their appendix removed in childhood.
Design Historical cohort study with computerised data and fertility data for this cohort and for an age matched cohort of women from the Swedish general population.
The cohorts were followed to 1994.
Participants 9840 women who were under 15 years when they underwent appendicectomy between 1964 and 1983 ; 47 590 control women.
Distributions of age at birth of first child among women with perforated and non-perforated appendix and women who underwent appendicectomy but were found to have a normal appendix compared with control women by using survival analysis methods.
Parity distributions at the latest update of the registry were also examined.
Results Women with a history of perforated appendix had a similar rate of first birth as the control women (adjusted hazard ratio 0.95 ; 95% confidence interval 0.88 to 1.04) and had a similar distribution of parity at the end of follow up.
Women who had had a normal appendix removed had an increased rate of first births (1.48 ; 1.42 to 1.54) and on average had their first child at an earlier age and reached a higher parity than control women.
Conclusion A history of perforated appendix in childhood does not seem to have long term negative consequences on female fertility. (...)
Mots-clés Pascal : Appendicectomie, Enfant, Homme, Etude cohorte, Epidémiologie, Avenir obstétrical, Fertilité, Adulte, Etude comparative, Appendicite, Histopathologie, Perforation, Parité, Age, Suède, Europe, Femelle, Appendice vermiculaire, Chirurgie, Appareil digestif pathologie, Intestin pathologie, Anatomopathologie
Mots-clés Pascal anglais : Appendectomy, Child, Human, Cohort study, Epidemiology, Obstetrical outcome, Fertility, Adult, Comparative study, Appendicitis, Histopathology, Perforation, Parity, Age, Sweden, Europe, Female, Vermiform appendix, Surgery, Digestive diseases, Intestinal disease, Pathology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0234965
Code Inist : 002B30A01A2. Création : 16/11/1999.