To determine the prevalence of serologic reactivity, the 1-year incidence of seroconversion, and the frequency of multiple infections, and their associations with symptoms in a group ofvolunteers at high risk for tick-borne infections in New York state.
We performed a seroepidemiologic study of Lyme borreliosis, 2 of the ehrlichioses, Rocky Mountain spotted fever, and babesiosis among 671 participants who lived or worked in a high-risk area (mainly in eastern Long Island, New York) for tick-borne diseases.
Sera were collected in the winters of 1994 and 1995.
Signs and symptoms of tick-borne disease were monitored monthly by mail and telephone.
Lyme borreliosis serologies were done by enzyme-linked immunosorbent assay and Western blot.
Rocky Mountain spotted fever serologies were initially screened using Dip-S-Ticks, followed by specific indirect immunofluorescence.
Ehrlichiosis serologies were determined by epifluorescent microscopy, as were antibodies to Babesia microti.
Of the 671 participants, 88 (13%) had antibodies to >=1 tick-borne organisms, including 34 (5% of the total) with antibodies to Borrelia burgdorferi.
Twenty-seven participants had evidence of exposure to B. burgdorferi at baseline.
Seven participants (1%) seroconverted during the course of the study, 5 of whom were symptomatic for Lyme borreliosis. (...)
Mots-clés Pascal : Fièvre à tique, Ehrlichiose, Rickettsialose, Bactériose, Infection, Epidémiologie, Prévalence, Séropositivité, Conversion, Association, Risque élevé, Homme, Nord est, Etats Unis, Amérique du Nord, Amérique, Parasitologie, Sérologie
Mots-clés Pascal anglais : Tick borne fever, Ehrlichia infection, Rickettsialosis, Bacteriosis, Infection, Epidemiology, Prevalence, Seropositivity, Conversion, Association, High risk, Human, Northeast, United States, North America, America, Parasitology, Serology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0234840
Code Inist : 002B05E05. Création : 16/11/1999.