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  1. Fulltext. Consanguinity and recurrence risk of stillbirth and infant death.

    Article - En anglais

    Fulltext.

    Objectives

    The aim of this study was to estimate the recurrence risk for stillbirth and infant death and compare results for offspring of first-cousin parents with results for offspring of unrelated parents.

    Methods

    The study population consisted of all single births with a previous sibling born in Norway between 1967 and 1994.

    Altogether, 629 888 births were to unrelated parents, and 3466 births were to parents who were first cousins.

    The risk of stillbirth and infant death was estimated for subsequent siblings contingent on parental consanguinity and survival of the previous sibling.

    Results

    For unrelated parents, the risk of early death (stillbirth plus infant death) for the subsequent sibling was 17 of 1000 if the previous child survived and 67 of 1000 if the previous child died before I year of age.

    For parents who were first cousins, the risk of early death for the subsequent sibling was 29 of 1000 if the previous child survived and 116 of 1000 if the previous child died.

    Conclusions

    The risk of recurrence of stillbirth and infant death is higher for offspring of first-cousin parents compared with offspring of unrelated parents.

    Mots-clés Pascal : Consanguinité, Parent, Mort né, Mort, Epidémiologie, Facteur risque, Récidive, Nourrisson, Homme, Norvège, Europe

    Mots-clés Pascal anglais : Consanguinity, Parent, Stillborn, Death, Epidemiology, Risk factor, Relapse, Infant, Human, Norway, Europe

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0227387

    Code Inist : 002B30A01A2. Création : 16/11/1999.