The incidence of non-Hodgkin's lymphoma (NHL), particularly at certain extranodal sites, has been demonstrated to be rising, at least in the USA, more than for any other malignancy.
One of the major sites of extranodal NHL is the gastrointestinal tract, though little is known of its epidemiological characteristics.
Over an 8-year period (1986 to 1993) 1069 primary gastrointestinal NHL cases were reported to the Leukaemia Research Fund Data Collection Survey which covers many parts of England and Wales.
Age-standardized incidence rates of gastrointestinal NHL at all sites (0.58/105 per year), gastric (0.24/105 per year), small bowel (0.17/105 per year) and large bowel (0.06/105 per year) confirmed that the UK has the lowest rates of gastrointestinal NHL in Europe.
An excess of males was observed at all ages and for all sites.
Time-trend analyses showed annual increases in incidence rates for gastric (6.3%) and small bowel (5.9%) NHL although a concomitant decrease in gastrointestinal NHL of unknown site suggested that at least part of these increases had resulted from more accurate diagnoses.
Overall, the incidence of gastrointestinal NHL significantly increased by 2.7% per annum and was limited to the population aged over 50 years in this series.
Mots-clés Pascal : Lymphome non hodgkinien, Gastrointestinal, Incidence, Epidémiologie, Registre, Angleterre, Grande Bretagne, Royaume Uni, Europe, Pays de Galles, Homme, Extraganglionnaire, Hémopathie maligne, Lymphoprolifératif syndrome, Estomac pathologie, Intestin pathologie, Appareil digestif pathologie
Mots-clés Pascal anglais : Non Hodgkin lymphoma, Gastrointestinal, Incidence, Epidemiology, Register, England, Great Britain, United Kingdom, Europe, Wales, Human, Extraganglionar, Malignant hemopathy, Lymphoproliferative syndrome, Gastric disease, Intestinal disease, Digestive diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0225907
Code Inist : 002B19B. Création : 16/11/1999.