Workers repairing jet engines had respiratory, rheumatic, and neurobehavioral symptoms.
They had welded and ground stainless steel parts using hard metal tools and cleaned metal with chlorinated and fluorinated organic solvents.
We compared 154 workers and 112 unexposed subjects, all volunteers of similar ages and with similar educational levels, for abnormalities on chest radiographs, spirometric measurements, and questionnaires.
Also appraised were performance of reaction time, balance, blink reflex latency, color discrimination, Culture Fair, vocabulary, slotted pegboard, trail making A and B, profile of mood states (POMS), and frequencies of 35 symptoms.
Compared to unexposed subjects, workers had significantly more respiratory symptoms but no differences in pulmonary function.
They had significantly prolonged simple and choice reaction time (P<0.0001), and abnormal balance with eyes open and eyes closed (P<0.0001), and abnormal color discrimination.
Blink reflex latency was abnormal in both exposed workers and in local unexposed compared to other reference groups.
Focus of the inquiry on lung disease helped ensure that for neurobehavioral tests confounding factors were minimal and known biases were small.
We tentatively attribute the neurobehavioral impairments and increased symptom frequencies to chlorinated solvent exposure.
Excessive respiratory symptoms are attributed to welding stainless steel combined with cigarette smoking. (...)
Mots-clés Pascal : Trichloroéthylène, Manganèse, Industrie aéronautique, Solvant organique, Clignement palpébral, Temps réaction, Toxicité, Appareil respiratoire pathologie, Rhumatisme, Poumon pathologie, Trouble comportement, Exposition professionnelle, Médecine travail, Milieu professionnel, Etude comparative, Homme, Sexe, Race, Age, Chlore Composé organique, Association toxique
Mots-clés Pascal anglais : Trichloroethylene, Manganese, Aeronautic industry, Organic solvent, Blinking, Reaction time, Toxicity, Respiratory disease, Rheumatism, Lung disease, Behavioral disorder, Occupational exposure, Occupational medicine, Occupational environment, Comparative study, Human, Sex, Race, Age, Chlorine Organic compounds, Toxic association
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0222900
Code Inist : 002B03L04. Création : 16/11/1999.