High prevalence of factor V Leiden in healthy Jordanian arabs.
The prevalence of APC resistance in healthy Jordanian Arabs was studied.
Between October 1996 through September 1997 a total of 400 healthy subjects were studied.
There were 212 males and 188 females.
APC resistance was studied by functional and DNA methods.
There were a total of 52 subjects (13%) who were APC resistant by the functional test.
There were 49 subjects (12.25%) who had FV Q506by DNA test.
Of these there were 42 heterozygous and 7 homozygous (allele frequency 0.07).
None of the subjects had clinical thrombosis.
It is concluded that the prevalence of APC resistance due to FV Q506 is high in Jordanian Arabs.
Mots-clés Pascal : Résistance, Protein C (activated), Serine endopeptidases, Peptidases, Hydrolases, Enzyme, Facteur V Leiden, Prévalence, Epidémiologie, Ethnie, Arabe, Jordanie, Asie, Homme, Hémopathie, Coagulopathie, Maladie héréditaire
Mots-clés Pascal anglais : Resistance, Protein C (activated), Serine endopeptidases, Peptidases, Hydrolases, Enzyme, Factor V Leiden, Prevalence, Epidemiology, Ethnic group, Arabic, Jordan, Asia, Human, Hemopathy, Coagulopathy, Genetic disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0220091
Code Inist : 002B19C. Création : 16/11/1999.