Background The effect of passive smoking on the risk of coronary heart disease is controversial.
We conducted a meta-analysis of the risk of coronary heart disease associated with passive smoking among nonsmokers.
Methods We searched the Medline and Dissertation Abstracts Online data bases and reviewed citations in relevant articles to identify 18 epidemiologic (10 cohort and 8 case-control) studies that met prestated inclusion criteria.
Information on the designs of the studies, the characteristics of the study subjects, exposure and outcome measures, control for potential confounding factors, and risk estimates was ed independently by three investigators using a standardized protocol.
Results Overall, nonsmokers exposed to environmental smoke had a relative risk of coronary heart disease of 1.25 (95 percent confidence interval, 1.17 to 1.32) as compared with nonsmokers not exposed to smoke.
Passive smoking was consistently associated with an increased relative risk of coronary heart disease in cohort studies (relative risk, 1.21 ; 95 percent confidence interval, 1.14 to 1.30), in case-control studies (relative risk, 1.51 ; 95 percent confidence interval, 1.26 to 1.81), in men (relative risk, 1.22 ; 95 percent confidence interval, 1.10 to 1.35), in women (relative risk, 1.24 ; 95 percent confidence interval, 1.15 to 1.34), and in those exposed to smoking at home (relative risk, 1.17 ; 95 percent confidence interval, 1.1 to 1.24) or in the workplace (relative risk, 1.11 (...)
Mots-clés Pascal : Cardiopathie coronaire, Epidémiologie, Facteur risque, Tabagisme passif, Prévalence, Impact environnement, Milieu familial, Métaanalyse, Analyse statistique, Revue bibliographique, Non fumeur, Homme, Etats Unis, Amérique du Nord, Amérique, Appareil circulatoire pathologie, Tabagisme, Prévention
Mots-clés Pascal anglais : Coronary heart disease, Epidemiology, Risk factor, Passive smoking, Prevalence, Environment impact, Family environment, Metaanalysis, Statistical analysis, Bibliographic review, Non smoker, Human, United States, North America, America, Cardiovascular disease, Tobacco smoking, Prevention
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0219960
Code Inist : 002B12A03. Création : 16/11/1999.