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  1. Contribution of modern cardiovascular treatment and risk factor changes to the decline in coronary heart disease mortality in Scotland between 1975 and 1994.

    Article - En anglais


    To estimate the fall in coronary heart disease (CHD) mortality in Scotland attributable to medical and surgical treatments, and risk factor changes, between 1975 and 1994.

    Design-A cohort model combining effectiveness data from meta-analyses with information on treatment uptake in all patient categories in Scotland.

    Setting and patients-The whole Scottish population of 5.1 million, including all patients with recognised CHD.

    Interventions-All cardiological, medical, and surgical treatments, and all risk factor changes between 1975 and 1994.

    Data were obtained from epidemiological surveys, routine National Health Service sources, and local audits.

    Main outcome measures-Deaths from CHD in 1975 and 1994.


    There were 15 234 deaths from CHD in 1994,6205 fewer deaths than expected if there had been no decline from 1975 mortality rates.

    In 1994, the total number of deaths prevented or postponed by all treatments and risk factor reductions was estimated at 6747 (minimum 4790, maximum 10 695).

    Forty per cent of this benefit was attributed to treatments (initial treatments for acute myocardial infarction 10%, treatments for hypertension 9%, for secondary prevention 8%, for heart failure 8%, aspirin for angina 2%, coronary artery bypass grafting surgery 2%, and angioplasty 0.1%). (...)

    Mots-clés Pascal : Cardiopathie coronaire, Ecosse, Grande Bretagne, Royaume Uni, Europe, Mortalité, Homme, Traitement, Facteur risque, Pronostic, Epidémiologie, Exploration, Evolution, Appareil circulatoire pathologie

    Mots-clés Pascal anglais : Coronary heart disease, Scotland, Great Britain, United Kingdom, Europe, Mortality, Human, Treatment, Risk factor, Prognosis, Epidemiology, Exploration, Evolution, Cardiovascular disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0219360

    Code Inist : 002B12A03. Création : 16/11/1999.