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  1. A case-control study on risk factors for pancreatic diseases in Kerala, India : Early detection and high risk of pancreatic cancer.

    Article - En anglais

    BACKGROUND/AIMS 

    We simultaneously conducted case-control studies, in Kerala of South India, on chronic calcific pancreatitis of the tropics (CCPT), pancreatic ductal adenocarcinoma (PDA) with CCPT, and PDA alone to assess similarity of and difference between their risk factors.

    METHODOLOGY 

    Cases with one of these diseases were identified at the Trivandrum Medical College (TMC) Hospital, in Kerala, from 1994 to 1996.

    Controls were selected from healthy hospital visitors of the TMC Hospital by individual age (within ±3 years) and sex-matched with the index case.

    Odds ratios and their 95% confidence intervals for potential risk factors were calculated.

    RESULTS 

    Frequent consumption of cassava was positively associated with the risk of PDA with CGPT.

    Heavy cigarette smoking and drinking large amounts of coffee and/or tea everyday were positively related to the risk of PDA alone.

    Frequent consumption of vegetables and/or fruits was correlated to the decreased risk of PDA alone.

    CONCLUSIONS 

    Risk factors as well as preventive factors seem to be different between PDA with CCPT and PDA alone.

    Further study is necessary, especially to clarify the prognostic factors which would induce pancreatic malignancy in patients with CCPT.

    Mots-clés Pascal : Pancréatite, Chronique, Calcification, Adénocarcinome, Pancréas, Complication, Facteur risque, Facteur prédictif, Evolution, Etude cas témoin, Homme, Inde, Asie, Appareil digestif pathologie, Pancréas pathologie, Tumeur maligne

    Mots-clés Pascal anglais : Pancreatitis, Chronic, Calcification, Adenocarcinoma, Pancreas, Complication, Risk factor, Predictive factor, Evolution, Case control study, Human, India, Asia, Digestive diseases, Pancreatic disease, Malignant tumor

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0213731

    Code Inist : 002B13C01. Création : 16/11/1999.