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  1. Occupational induction of hypersensitivity after an accidental exposure to chloromethylisothiazolinone and methylisothiazolinone (CMI/MI) in an industrial worker.

    Article - En anglais

    A process worker in a paper chemical plant developed an immediate local dermal irritation and delayed bullous dermatitis due to induction of hypersensitivity following an accidental exposure to chloromethylisothiazolinone and methylisothiazolinone (CMI/MI) biocide.

    Contact allergy to the isothiazolinone mixture was confirmed by skin patch testing.

    The dermatitis healed in four weeks, and the worker was advised to avoid all CMI/MI containing products.

    In a one-year follow-up he did not present with any further skin symptoms.

    Preventive measures are important for avoiding induction of hypersensitivity to concentrated CMI/MI solutions in industrial workers.

    Mots-clés Pascal : Exposition professionnelle, Médecine travail, Etude cas, Dermatite contact, Homme, Allergie, Etude longitudinale, Hypersensibilité contact, Industrie chimique, Thiazole dérivé, Antimicrobien, Peau pathologie, Immunopathologie

    Mots-clés Pascal anglais : Occupational exposure, Occupational medicine, Case study, Contact dermatitis, Human, Allergy, Follow up study, Contact hypersensitivity, Chemical industry, Thiazole derivatives, Antimicrobial agent, Skin disease, Immunopathology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0213673

    Code Inist : 002B03L06. Création : 16/11/1999.