A process worker in a paper chemical plant developed an immediate local dermal irritation and delayed bullous dermatitis due to induction of hypersensitivity following an accidental exposure to chloromethylisothiazolinone and methylisothiazolinone (CMI/MI) biocide.
Contact allergy to the isothiazolinone mixture was confirmed by skin patch testing.
The dermatitis healed in four weeks, and the worker was advised to avoid all CMI/MI containing products.
In a one-year follow-up he did not present with any further skin symptoms.
Preventive measures are important for avoiding induction of hypersensitivity to concentrated CMI/MI solutions in industrial workers.
Mots-clés Pascal : Exposition professionnelle, Médecine travail, Etude cas, Dermatite contact, Homme, Allergie, Etude longitudinale, Hypersensibilité contact, Industrie chimique, Thiazole dérivé, Antimicrobien, Peau pathologie, Immunopathologie
Mots-clés Pascal anglais : Occupational exposure, Occupational medicine, Case study, Contact dermatitis, Human, Allergy, Follow up study, Contact hypersensitivity, Chemical industry, Thiazole derivatives, Antimicrobial agent, Skin disease, Immunopathology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0213673
Code Inist : 002B03L06. Création : 16/11/1999.