In our study, we estimated formaldehyde exposure levels of Korean medical students during their cadaver dissection practice hours.
In addition, we examined the prevalence rates of formaldehyde-specific immunoglobulin E or immunoglobulin G antibodies and compared the results with the symptoms the students experienced as a result of formaldehyde exposure.
There were 167 Korean medical students (i.e., subjects) aged 23.8 ± 2.5 y (mean ± standard deviation) and a control group of 67 premedical students aged 20.1 ± 2.8 y (mean ± standard deviation).
Concentrations of formaldehyde in the cadaver dissection practice laboratory ranged from 0.194 to 11.245 mg/m3 (3.736 ± 3.478 mg/m3 [mean ±standard deviation]). Students reported by self-administered questionnaires that eye soreness (92.8%) and lacrimation (74.9%) were the most common symptoms they experienced during the laboratory sessions.
One (0.6%) of the 167 medical students had a history of wheezing during dissection.
Fourteen (8.4%) had specific immunoglobulin G antibody, but none had specific immunoglobulin E antibody.
These results suggest that (a) Korean medical students are exposed to formaldehyde at a relatively high levels in their dissection practice hours, (b) specific immunoglobulin G is not related to adverse eye or respiratory symptoms, and (c) specific immunoglobulin E is rarely induced as a result of exposure to formaldehyde.
Mots-clés Pascal : Formaldéhyde, Exposition professionnelle, Toxicité, Immunopathologie, Anticorps, Sang, Homme, Etudiant, Spécialité médicale, Corée, Asie, Relation dose réponse, Sérumalbumine, Médecine travail, Epidémiologie
Mots-clés Pascal anglais : Formaldehyde, Occupational exposure, Toxicity, Immunopathology, Antibody, Blood, Human, Student, Medical specialty, Korea, Asia, Dose activity relation, Serum albumin, Occupational medicine, Epidemiology
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0212581
Code Inist : 002B03L06. Création : 16/11/1999.